CHARACTERIZING THE MECHANISMS BY WHICH NEUROPILIN-1 AND ITS LIGANDS REGULATE INTEGRIN FUNCTION: IMPLICATIONS FOR VASCULAR DEVELOPMENT

Scientific Publications

• 2012 CELL RESEARCH

  The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling

• 2013 JOURNAL OF CELL BIOLOGY

  Polarity, cell division, and out-of-equilibrium dynamics control the growth of epithelial structures

• 2012 CURRENT OPINION IN CELL BIOLOGY

  Regulation of adhesion site dynamics by integrin traffic

• 2011 MOLECULAR ASPECTS OF MEDICINE

  Increasing traffic on vascular routes

• 2011 Molecular BioSystems

  Regulation of integrins by conformation and traffic: it takes two to tango

• 2012 JOURNAL OF CLINICAL INVESTIGATION

  Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice

• 2009 EUROPEAN CYTOKINE NETWORK

  Angiogenesis: a balancing act between integrin activation and inhibition?

• 2012 JOURNAL OF CELL BIOLOGY

  The vesicular SNARE Synaptobrevin is required for Semaphorin 3A axonal repulsion

• 2013 JOURNAL OF INTERNAL MEDICINE

  Class 3 semaphorins: physiological vascular normalizing agents for anti-cancer therapy

• 2011 INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

  Nervous vascular parallels: axon guidance and beyond

• 2016 NATURE COMMUNICATIONS

  PPFIA1 drives active a5ß1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis

• 2009 JOURNAL OF CLINICAL INVESTIGATION

  Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models