ROLE OF P63 AND FAMILY MEMBERS IN EEC SYNDROME: MOLECULAR MECHANISMS AND IN VIVO EFFECTS

Scientific Publications

• 2006 CELL CYCLE

  Degradation of p63 by Itch

• 2002 FASEB JOURNAL

  Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient

• 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

  p73: in silico evidence for a putative third promoter region

• 2002 NATURE REVIEWS CANCER

  p73: Friend or foe in tumorigenesis

• 2001 CELL DEATH AND DIFFERENTIATION

  Human Delta Np73 regulates a dominant negative feedback loop for TAp73 and p53

• 2004 ONCOGENE

  p73-alpha is capable of inducing scotin and ER stress

• 2005 EMBO JOURNAL

  The ubiquitin-protein ligase Itch regulates p73 stability

• 2004 CELL DEATH AND DIFFERENTIATION

  DNA damage induces the rapid and selective degradation of the Delta Np73 isoform, allowing apoptosis to occur

• 2004 ONCOGENE

  Regulation of the apoptosis-necrosis switch